Quantification of Arachidonic Acid and Its Metabolites in Rat Tissues by UHPLC-MS/MS: Application for the Identification of Potential Biomarkers of Benign Prostatic Hyperplasia

To evaluate the potential relationship between benign prostatic hyperplasia (BPH) and the arachidonic acid (AA) metabolome, a UHPLC—MS/MS method has been developed and validated for simultaneous determination of AA and its cyclooxygenase(COX) and lipoxygenase(LOX) pathway metabolites (15-HETE, 12-HE...

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Detalles Bibliográficos
Autores principales: Bian, Qiaoxia, Wang, Weihui, Wang, Nannan, Peng, Yan, Ma, Wen, Dai, Ronghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125601/
https://www.ncbi.nlm.nih.gov/pubmed/27893755
http://dx.doi.org/10.1371/journal.pone.0166777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125601/
https://www.ncbi.nlm.nih.gov/pubmed/27893755
http://dx.doi.org/10.1371/journal.pone.0166777

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