Cargando…

Quantification of Arachidonic Acid and Its Metabolites in Rat Tissues by UHPLC-MS/MS: Application for the Identification of Potential Biomarkers of Benign Prostatic Hyperplasia

To evaluate the potential relationship between benign prostatic hyperplasia (BPH) and the arachidonic acid (AA) metabolome, a UHPLC—MS/MS method has been developed and validated for simultaneous determination of AA and its cyclooxygenase(COX) and lipoxygenase(LOX) pathway metabolites (15-HETE, 12-HE...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bian, Qiaoxia, Wang, Weihui, Wang, Nannan, Peng, Yan, Ma, Wen, Dai, Ronghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125601/ https://www.ncbi.nlm.nih.gov/pubmed/27893755 http://dx.doi.org/10.1371/journal.pone.0166777

Ejemplares similares

Screening, quantification, and confirmation of synthetic cannabinoid metabolites in urine by UHPLC–QTOF–MS
por: Gundersen, Per Ole M., et al.
Publicado: (2018)

Comparison of Two Methods, UHPLC-UV and UHPLC-MS/MS, for the Quantification of Polyphenols in Cider Apple Juices
por: Verdu, Cindy F., et al.
Publicado: (2013)

Quantitative determination of vitamin D metabolites in plasma using UHPLC-MS/MS
por: Ding, Shujing, et al.
Publicado: (2010)

Quantification of Sterol and Triterpenol Biomarkers in Sediments of the Cananéia-Iguape Estuarine-Lagoonal System (Brazil) by UHPLC-MS/MS
por: Bataglion, Giovana Anceski, et al.
Publicado: (2016)

Identification and Pharmacokinetic Studies on Complanatuside and Its Major Metabolites in Rats by UHPLC-Q-TOF-MS/MS and LC-MS/MS
por: Yao, Yu-Feng, et al.
Publicado: (2018)

Identification for metabolism profiles and pharmacokinetic studies of tradition Chinese prescription Ji-Ming-San and its major metabolites in rats by UHPLC-Q-TOF-MS/MS and UHPLC-MS/MS
por: Hsieh, Cheng-Yang, et al.
Publicado: (2023)

Secondary Metabolite Profiling of Species of the Genus Usnea by UHPLC-ESI-OT-MS-MS
por: Salgado, Francisco, et al.
Publicado: (2017)

Identification of Metabolites of Eupatorin in Vivo and in Vitro Based on UHPLC-Q-TOF-MS/MS
por: Li, Luya, et al.
Publicado: (2019)

Pharmacokinetic Study and Metabolite Identification of CAM106 in Rats by Validated UHPLC-MS/MS
por: Xi, Ruqi, et al.
Publicado: (2023)

An UHPLC-MS/MS method for quantification of the CDK4/6 inhibitor abemaciclib in human serum
por: Habler, Katharina, et al.
Publicado: (2022)

Simultaneous quantification of eight hemoglobin adducts of genotoxic substances by isotope-dilution UHPLC-MS/MS
por: Gauch, Fabian, et al.
Publicado: (2022)

A Novel UHPLC-MS/MS Method for the Quantification of Seven Opioids in Different Human Tissues
por: Manca, Alessandra, et al.
Publicado: (2023)

Determination of the Synthetic Cannabinoids JWH-122, JWH-210, UR-144 in Oral Fluid of Consumers by GC-MS and Quantification of Parent Compounds and Metabolites by UHPLC-MS/MS
por: La Maida, Nunzia, et al.
Publicado: (2020)

UHPLC–MS/MS-Based Nontargeted Metabolomics Analysis Reveals Biomarkers Related to the Freshness of Chilled Chicken
por: Zhang, Tao, et al.
Publicado: (2020)

Dynamic profiling of intact glucosinolates in radish by combining UHPLC-HRMS/MS and UHPLC-QqQ-MS/MS
por: Yan, Chenghuan, et al.
Publicado: (2023)

Simultaneous Quantification and Pharmacokinetic Study of Five Homologs of Dalbavancin in Rat Plasma Using UHPLC-MS/MS
por: Zhu, Difeng, et al.
Publicado: (2020)

A Rapid and Simple UHPLC-MS/MS Method for Quantification of Plasma Globotriaosylsphingosine (lyso-Gb3)
por: Perrone, Alessandro, et al.
Publicado: (2021)

Determination of Paraquat in Arabidopsis Tissues and Protoplasts by UHPLC-MS/MS
por: Zhao, Mingming, et al.
Publicado: (2023)

Identification and Quantification of Coumarins by UHPLC-MS in Arabidopsis thaliana Natural Populations
por: Perkowska, Izabela, et al.
Publicado: (2021)

New Method of Analysis of Nitrofurans and Nitrofuran Metabolites in Different Biological Matrices Using UHPLC-MS/MS
por: Śniegocki, Tomasz, et al.
Publicado: (2018)

Development of a Multimatrix UHPLC-MS/MS Method for the Determination of Paracetamol and Its Metabolites in Animal Tissues
por: Pietruk, Konrad, et al.
Publicado: (2021)

Screening and Identification of the Main Metabolites of Schisantherin a In Vivo and In Vitro by Using UHPLC-Q-TOF-MS/MS
por: Feng, Wei, et al.
Publicado: (2020)

An integrated strategy of MS-network-based offline 2DLC-QTOF-MS/MS coupled with UHPLC-QTRAP(®)-MS/MS for the characterization and quantification of the non-polysaccharides in Sijunzi decoction
por: Dong, Bangjian, et al.
Publicado: (2021)

Pharmacokinetics and Metabolism Study of Deep-Sea-Derived Butyrolactone I in Rats by UHPLC–MS/MS and UHPLC–Q-TOF-MS
por: Wu, Liang, et al.
Publicado: (2021)

Quantification of Apixaban, Dabigatran, Edoxaban, and Rivaroxaban in Human Serum by UHPLC-MS/MS—Method Development, Validation, and Application
por: Lindahl, Sofia, et al.
Publicado: (2018)

Development of a UHPLC-MS/MS method for the quantification of ilaprazole enantiomers in rat plasma and its pharmacokinetic application
por: Ou, Fengting, et al.
Publicado: (2020)

Development and Validation of a Reliable UHPLC-MS/MS Method for Simultaneous Quantification of Macrocyclic Lactones in Bovine Plasma
por: Zeleke, Gemechu, et al.
Publicado: (2022)

Acetonitrile Adducts of Tranexamic Acid as Sensitive Ions for Quantification at Residue Levels in Human Plasma by UHPLC-MS/MS
por: Silva, Eduarda M. P., et al.
Publicado: (2021)

Quantification of 17 Endogenous and Exogenous Steroidal Hormones in Equine and Bovine Blood for Doping Control with UHPLC-MS/MS
por: Caprioli, Giovanni, et al.
Publicado: (2021)

Pharmacokinetics and Metabolism Research of Shenkang Injection in Rats Based on UHPLC-MS/MS and UHPLC-Q-Orbitrap HRMS
por: Jiang, Xiaofang, et al.
Publicado: (2020)

Secondary Metabolites in Ramalina terebrata Detected by UHPLC/ESI/MS/MS and Identification of Parietin as Tau Protein Inhibitor
por: Cornejo, Alberto, et al.
Publicado: (2016)

UHPLC-MS/MS Analysis of Cannabidiol and Its Metabolites in Serum of Patients with Resistant Epilepsy Treated with CBD Formulations
por: Malaca, Sara, et al.
Publicado: (2021)

Multi-Residue Analysis of Fipronil and Its Metabolites in Eggs by SinChERS-Based UHPLC-MS/MS
por: Han, Keguang, et al.
Publicado: (2021)

Metabolite Identification of Isopropoxy Benzene Guanidine in Rat Liver Microsomes by Using UHPLC-Q-TOF-MS/MS
por: Lu, Yixing, et al.
Publicado: (2023)

Determination of iohexol by capillary blood microsampling and UHPLC-MS/MS
por: Ion, Valentin, et al.
Publicado: (2019)

Development and Validation of a UHPLC–MS/MS Method for the Quantification of a Novel PYGB Inhibitor in Plasma: Application to Pharmacokinetic Studies
por: Xu, Sumei, et al.
Publicado: (2023)

HPLC–PDA Polyphenolic Quantification, UHPLC–MS Secondary Metabolite Composition, and In Vitro Enzyme Inhibition Potential of Bougainvillea glabra
por: Saleem, Hammad, et al.
Publicado: (2020)

Simultaneous quantification of nine aconitum alkaloids in Aconiti Lateralis Radix Praeparata and related products using UHPLC–QQQ–MS/MS
por: He, Fan, et al.
Publicado: (2017)

Automatic analytical approach for the determination of 12 illicit drugs and nicotine metabolites in wastewater using on-line SPE-UHPLC-MS/MS
por: Wang, Jingyuan, et al.
Publicado: (2021)

Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs
por: Wang, Lin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mo151jsi7cqm4ql82vc28i17o3