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Solid-Phase Synthesis of ɤ-Lactone and 1,2-Oxazine Derivatives and Their Efficient Chiral Analysis

Derivatives of 3-methyl-3,6-dihydro-2H-1,2-oxazine-6-carboxylic acid prepared by regioselective hetero Diels-Alder reaction of arylnitroso compounds with sorbic acid were used for solid-phase synthesis of a library of derivatives that included modification of carboxylic group, dihydroxylation of dou...

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Detalles Bibliográficos
Autores principales: Krupkova, Sona, Aguete, Gonzalo Pazos, Kocmanova, Leona, Volna, Tereza, Grepl, Martin, Novakova, Lucie, Miller, Marvin John, Hlavac, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125624/
https://www.ncbi.nlm.nih.gov/pubmed/27893812
http://dx.doi.org/10.1371/journal.pone.0166558