Beneficial Effects of Metformin and/or Salicylate on Palmitate- or TNFα-Induced Neuroinflammatory Marker and Neuropeptide Gene Regulation in Immortalized NPY/AgRP Neurons

Neuropeptide Y (NPY)/Agouti-related peptide (AgRP)-expressing neurons in the hypothalamus induce feeding and decrease energy expenditure. With consumption of a diet high in fat, there is an increase in circulating saturated free fatty acids, including palmitate, leading to the development of neuroin...

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Detalles Bibliográficos
Autores principales: Ye, Wenqing, Ramos, Ernesto H., Wong, Brian C., Belsham, Denise D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125651/
https://www.ncbi.nlm.nih.gov/pubmed/27893782
http://dx.doi.org/10.1371/journal.pone.0166973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125651/
https://www.ncbi.nlm.nih.gov/pubmed/27893782
http://dx.doi.org/10.1371/journal.pone.0166973

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