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Role of PTEN in Oxidative Stress and DNA Damage in the Liver of Whole-Body Pten Haplodeficient Mice

Type 2 diabetes (T2DM) and obesity are frequently associated with non-alcoholic fatty liver disease (NAFLD) and with an elevated cancer incidence. The molecular mechanisms of carcinogenesis in this context are only partially understood. High blood insulin levels are typical in early T2DM and excessi...

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Detalles Bibliográficos
Autores principales: Bankoglu, Ezgi Eyluel, Tschopp, Oliver, Schmitt, Johannes, Burkard, Philipp, Jahn, Daniel, Geier, Andreas, Stopper, Helga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125655/
https://www.ncbi.nlm.nih.gov/pubmed/27893783
http://dx.doi.org/10.1371/journal.pone.0166956