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Simulating Next-Generation Sequencing Datasets from Empirical Mutation and Sequencing Models
An obstacle to validating and benchmarking methods for genome analysis is that there are few reference datasets available for which the “ground truth” about the mutational landscape of the sample genome is known and fully validated. Additionally, the free and public availability of real human genome...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125660/ https://www.ncbi.nlm.nih.gov/pubmed/27893777 http://dx.doi.org/10.1371/journal.pone.0167047 |