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Synthetic high-density lipoproteins for delivery of 10-hydroxycamptothecin

The purpose of this study was to develop a novel synthetic high-density lipoprotein (sHDL) nanoparticle delivery system for 10-hydroxycamptothecin (HCPT) for treatment of colon carcinoma. HDL is recognized by scavenger receptor B-I (SR-BI) over-expressed in colon carcinomas 5- to 35-fold relative to...

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Detalles Bibliográficos
Autores principales: Yuan, Yue, Wen, Jian, Tang, Jie, Kan, Qiming, Ackermann, Rose, Olsen, Karl, Schwendeman, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125756/
https://www.ncbi.nlm.nih.gov/pubmed/27920529
http://dx.doi.org/10.2147/IJN.S112835