Meta-analysis of the impact of thioprine S-methyltransferase polymorphisms on the tolerable 6-mercaptopurine dose considering initial dose and ethnic difference

A meta-analysis was conducted to decide whether to reduce an initial 6-mercaptopurine (6-MP) dose in TPMT heterozygote in the case of an initial 6-MP dose of <75 mg/m(2)/d and to compare the tolerable 6-MP dose among different ethnic groups. The study was undertaken according to Preferred Reporti...

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Detalles Bibliográficos
Autores principales: Kim, Myeong Gyu, Ko, Minoh, Kim, In-Wha, Oh, Jung Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125793/
https://www.ncbi.nlm.nih.gov/pubmed/27920553
http://dx.doi.org/10.2147/OTT.S110800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125793/
https://www.ncbi.nlm.nih.gov/pubmed/27920553
http://dx.doi.org/10.2147/OTT.S110800

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