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Design, synthesis and evaluation of VEGF-siRNA/CRS as a novel vector for gene delivery
Small interfering RNA (siRNA) delivery is a prospective method in gene therapy, but it has application limitations such as negative charge, water solubility and high molecular weight. In this study, a safe and efficient nano-vector, CRS, was designed and synthesized to facilitate siRNA delivery. Phy...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125806/ https://www.ncbi.nlm.nih.gov/pubmed/27920500 http://dx.doi.org/10.2147/DDDT.S118461 |