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Hepatitis C virus NS3‐4A inhibits the peroxisomal MAVS‐dependent antiviral signalling response

Hepatitis C virus (HCV) is the cause of one of the most prevalent viral infections worldwide. Upon infection, the HCV genome activates the RIG‐I‐MAVS signalling pathway leading to the production of direct antiviral effectors which prevent important steps in viral propagation. MAVS localizes at perox...

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Detalles Bibliográficos
Autores principales: Ferreira, Ana R., Magalhães, Ana C., Camões, Fátima, Gouveia, Ana, Vieira, Marta, Kagan, Jonathan C., Ribeiro, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125814/
https://www.ncbi.nlm.nih.gov/pubmed/26865163
http://dx.doi.org/10.1111/jcmm.12801