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Allele-Specific Phenotype Suggests a Possible Stimulatory Activity of RCAN-1 on Calcineurin in Caenorhabditis elegans

Regulator of calcineurin 1 (RCAN1) binds to calcineurin through the PxIxIT motif, which is evolutionarily conserved. SP repeat phosphorylation in RCAN1 is required for its complete function. The specific interaction between RCAN1 and calcineurin is critical for calcium/calmodulin-dependent regulatio...

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Detalles Bibliográficos
Autores principales: Li, Weixun, Choi, Tae-Woo, Ahnn, Joohong, Lee, Sun-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125939/
https://www.ncbi.nlm.nih.gov/pubmed/27871170
http://dx.doi.org/10.14348/molcells.2016.0222