Cargando…

Allele-Specific Phenotype Suggests a Possible Stimulatory Activity of RCAN-1 on Calcineurin in Caenorhabditis elegans

Regulator of calcineurin 1 (RCAN1) binds to calcineurin through the PxIxIT motif, which is evolutionarily conserved. SP repeat phosphorylation in RCAN1 is required for its complete function. The specific interaction between RCAN1 and calcineurin is critical for calcium/calmodulin-dependent regulatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Weixun, Choi, Tae-Woo, Ahnn, Joohong, Lee, Sun-Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125939/ https://www.ncbi.nlm.nih.gov/pubmed/27871170 http://dx.doi.org/10.14348/molcells.2016.0222

Ejemplares similares

Regulator of Calcineurin (RCAN): Beyond Down Syndrome Critical Region
por: Lee, Sun-Kyung, et al.
Publicado: (2020)

Morphological Characterization of small, dumpy, and long Phenotypes in Caenorhabditis elegans
por: Cho, Joshua Young, et al.
Publicado: (2021)

Calcineurin tax-6 regulates male ray development and counteracts with kin-29 kinase in Caenorhabditis elegans
por: Kim, Seung Hyun, et al.
Publicado: (2019)

Human Endogenous Retrovirus K (HERV-K) can drive gene expression as a promoter in Caenorhabditis elegans
por: Durnaoglu, Serpen, et al.
Publicado: (2020)

Dicarbonyl/L-xylulose reductase (DCXR) producing xylitol regulates egg retention through osmolality control in Caenorhabditis elegans
por: Kim, Yuh-Nam, et al.
Publicado: (2022)

RCAN1-mediated calcineurin inhibition as a target for cancer therapy
por: Lao, Mengyi, et al.
Publicado: (2022)

Calcineurin Antagonizes AMPK to Regulate Lipolysis in Caenorhabditis elegans
por: Wang, Yanli, et al.
Publicado: (2017)

The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin
por: Li, Yang, et al.
Publicado: (2020)

A spontaneous complex structural variant in rcan-1 increases exploratory behavior and laboratory fitness of Caenorhabditis elegans
por: Zhao, Yuehui, et al.
Publicado: (2020)

The regulator of calcineurin (RCAN1) an important factor involved in atherosclerosis and cardiovascular diseases development
por: Torac, E, et al.
Publicado: (2014)

The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs
por: Huang, Bao, et al.
Publicado: (2020)

Novel Findings of Anti-Filarial Drug Target and Structure-Based Virtual Screening for Drug Discovery
por: Choi, Tae-Woo, et al.
Publicado: (2018)

Regulator of calcineurin 1 (Rcan1) has a protective role in brain ischemia/reperfusion injury
por: Sobrado, Mónica, et al.
Publicado: (2012)

RCAN1.4 suppresses the osteosarcoma growth and metastasis via interfering with the calcineurin/NFAT signaling pathway
por: Huang, Bao, et al.
Publicado: (2021)

Verapamil extends lifespan in Caenorhabditis elegans by inhibiting calcineurin activity and promoting autophagy
por: Liu, Wenwen, et al.
Publicado: (2020)

Covalent NEDD8 Conjugation Increases RCAN1 Protein Stability and Potentiates Its Inhibitory Action on Calcineurin
por: Noh, Eun Hye, et al.
Publicado: (2012)

RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2
por: Zhang, Jianjian, et al.
Publicado: (2021)

Syncytin, envelope protein of human endogenous retrovirus (HERV): no longer ‘fossil’ in human genome
por: Durnaoglu, Serpen, et al.
Publicado: (2022)

Human Endogenous Retroviruses as Gene Expression Regulators: Insights from Animal Models into Human Diseases
por: Durnaoglu, Serpen, et al.
Publicado: (2021)

Botulinum Toxin as a Pain Killer: Players and Actions in Antinociception
por: Kim, Dong-Wan, et al.
Publicado: (2015)

Human Endogenous Retroviruses: Friends and Foes in Urology Clinics
por: Lee, Sun-Kyung, et al.
Publicado: (2022)

Caenorhabditis elegans che-5 is allelic to gcy-22
por: Kunitomo, Hirofumi, et al.
Publicado: (2020)

CAMKII and Calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16
por: Tao, Li, et al.
Publicado: (2013)

Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling
por: Segref, Alexandra, et al.
Publicado: (2022)

Cynanchi atrati and Its Phenolic Constituent Sinapic Acid Target Regulator of Calcineurin 1 (RCAN1) to Control Skin Inflammation
por: Kim, Seon Sook, et al.
Publicado: (2022)

Molecular lesions in alleles of the Caenorhabditis elegans lin-11 gene
por: Young, Adrie F., et al.
Publicado: (2022)

Growth hormone increases regulator of calcineurin 1-4 (Rcan1-4) mRNA through c-JUN in rat liver
por: Nakata, Tomoko, et al.
Publicado: (2020)

Spatiotemporal expression of RCAN1 and its isoform RCAN1-4 in the mouse hippocampus after pilocarpine-induced status epilepticus
por: Cho, Kyung-Ok, et al.
Publicado: (2020)

Identification and Characterization of a Novel Allele of Caenorhabditis elegans bbs-7
por: Braunreiter, Kara, et al.
Publicado: (2014)

The regulator of calcineurin 1 (RCAN1) inhibits nuclear factor kappaB signaling pathway and suppresses human malignant glioma cells growth
por: Chen, Xin, et al.
Publicado: (2017)

Correlations of Genotype with Climate Parameters Suggest Caenorhabditis elegans Niche Adaptations
por: Evans, Kathryn S., et al.
Publicado: (2016)

VEGF Stimulates RCAN1.4 Expression in Endothelial Cells via a Pathway Requiring Ca(2+)/Calcineurin and Protein Kinase C-δ
por: Holmes, Katherine, et al.
Publicado: (2010)

Histone Deacetylase 3 Promotes RCAN1 Stability and Nuclear Translocation
por: Han, Kyung Ah, et al.
Publicado: (2014)

Gel-free genotyping of deletion alleles in Caenorhabditis elegans with real-time PCR
por: Wimberly, Keon, et al.
Publicado: (2020)

Computer-Assisted Transgenesis of Caenorhabditis elegans for Deep Phenotyping
por: Gilleland, Cody L., et al.
Publicado: (2015)

Caenorhabditis Elegans
Publicado: (2000)

RCANs regulate the convergent roles of NFATc1 in bone homeostasis
por: Kim, Jung Ha, et al.
Publicado: (2016)

Microfluidic approaches for Caenorhabditis elegans research
por: Levine, Erel, et al.
Publicado: (2020)

The synaptic organization in the Caenorhabditis elegans neural network suggests significant local compartmentalized computations
por: Ruach, Rotem, et al.
Publicado: (2023)

RNA interference may result in unexpected phenotypes in Caenorhabditis elegans
por: De-Souza, Evandro A, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_hkltvo7i72f1odod4e5kdac8of