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Fluorescence‐ and bioluminescence‐based approaches to study GPCR ligand binding
Ligand binding is a vital component of any pharmacologist's toolbox and allows the detailed investigation of how a molecule binds to its receptor. These studies enable the experimental determination of binding affinity of labelled and unlabelled compounds through kinetic, saturation (K(d)) and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125978/ https://www.ncbi.nlm.nih.gov/pubmed/26317175 http://dx.doi.org/10.1111/bph.13316 |