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The pharmacokinetics of vancomycin during the initial loading dose in patients with septic shock

OBJECTIVE: To characterize the pharmacokinetics (PK) of vancomycin in patients in the initial phase of septic shock. METHODS: Twelve patients with septic shock received an intravenous infusion of vancomycin 30 mg/kg over 2 h. The vancomycin PK study was conducted during the first 12 h of the regimen...

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Detalles Bibliográficos
Autores principales: Katip, Wasan, Jaruratanasirikul, Sutep, Pattharachayakul, Sutthiporn, Wongpoowarak, Wibul, Jitsurong, Arnurai, Lucksiri, Aroonrut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125998/
https://www.ncbi.nlm.nih.gov/pubmed/27920562
http://dx.doi.org/10.2147/IDR.S121513