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Estimation of the HIV-1 backward mutation rate from transmitted drug-resistant strains

One of the serious threats facing the administration of antiretroviral therapy to human immunodeficiency virus (HIV-1) infected patients is the reported increasing prevalence of transmitted drug resistance. However, given that HIV-1 drug-resistant strains are often less fit than the wild-type strain...

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Detalles Bibliográficos
Autores principales: Kitayimbwa, J.M., Mugisha, J.Y.T., Saenz, R.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126109/
https://www.ncbi.nlm.nih.gov/pubmed/27553875
http://dx.doi.org/10.1016/j.tpb.2016.08.001