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Critical Roles of Kupffer Cells in the Pathogenesis of Alcoholic Liver Disease: From Basic Science to Clinical Trials

Alcoholic liver disease (ALD) encompasses a spectrum of liver injury ranging from steatosis to steatohepatitis, fibrosis, and finally cirrhosis. Accumulating evidences have demonstrated that Kupffer cells (KCs) play critical roles in the pathogenesis of both chronic and acute ALD. It has become clea...

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Detalles Bibliográficos
Autores principales: Zeng, Tao, Zhang, Cui-Li, Xiao, Mo, Yang, Rui, Xie, Ke-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126119/
https://www.ncbi.nlm.nih.gov/pubmed/27965666
http://dx.doi.org/10.3389/fimmu.2016.00538