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Data file of a deep proteome analysis of the prefrontal cortex in aged mice with progranulin deficiency or neuronal overexpression of progranulin

Progranulin deficiency is associated with neurodegeneration in humans and in mice. The mechanisms likely involve progranulin-promoted removal of protein waste via autophagy. We performed a deep proteomic screen of the pre-frontal cortex in aged (13–15 months) female progranulin-deficient mice (GRN(−...

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Detalles Bibliográficos
Autores principales: Heidler, Juliana, Hardt, Stefanie, Wittig, Ilka, Tegeder, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126127/
https://www.ncbi.nlm.nih.gov/pubmed/27921079
http://dx.doi.org/10.1016/j.dib.2016.11.030