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Data file of a deep proteome analysis of the prefrontal cortex in aged mice with progranulin deficiency or neuronal overexpression of progranulin
Progranulin deficiency is associated with neurodegeneration in humans and in mice. The mechanisms likely involve progranulin-promoted removal of protein waste via autophagy. We performed a deep proteomic screen of the pre-frontal cortex in aged (13–15 months) female progranulin-deficient mice (GRN(−...
Autores principales: | Heidler, Juliana, Hardt, Stefanie, Wittig, Ilka, Tegeder, Irmgard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126127/ https://www.ncbi.nlm.nih.gov/pubmed/27921079 http://dx.doi.org/10.1016/j.dib.2016.11.030 |
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