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Gene therapy based on interleukin-12 loaded chitosan nanoparticles in a mouse model of fibrosarcoma
OBJECTIVE(S): Interleukin-12 (IL-12) as a cytokine has been proved to have a critical role in stimulating the immune system and has been used as immunotherapeutic agents in cancer gene therapy. Chitosan as a polymer, with high ability of binding to nucleic acids is a good candidate for gene delivery...
Autores principales: | Soofiyani, Saiedeh Razi, Hallaj-Nezhadi, Somayeh, Lotfipour, Farzaneh, Hosseini, Akbar Mohammad, Baradaran, Behzad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126226/ https://www.ncbi.nlm.nih.gov/pubmed/27917281 |
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