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VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts

ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family is known to play an important role in the pathogenesis of osteoarthritis (OA), working on aggrecan degradation or altering the integrity of extracellular matrix (ECM). Thus, the main purpose of our study was to define the...

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Detalles Bibliográficos
Autores principales: Pérez‐García, Selene, Carrión, Mar, Gutiérrez‐Cañas, Irene, González‐Álvaro, Isidoro, Gomariz, Rosa P., Juarranz, Yasmina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126260/
https://www.ncbi.nlm.nih.gov/pubmed/26818776
http://dx.doi.org/10.1111/jcmm.12777