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CD4(+) T Cell Fate in Glomerulonephritis: A Tale of Th1, Th17, and Novel Treg Subtypes

Multiple studies have identified CD4(+) T cells as central players of glomerulonephritis (GN). Cells of the Th1 and Th17 responses cause renal tissue damage, while Tregs mediate protection. Recently, a high degree of plasticity among these T cell lineages was proposed. During inflammation, Th17 cell...

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Detalles Bibliográficos
Autores principales: Krebs, Christan F., Steinmetz, Oliver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126430/
https://www.ncbi.nlm.nih.gov/pubmed/27974866
http://dx.doi.org/10.1155/2016/5393894