Global gene regulation during activation of immunoglobulin class switching in human B cells

Immunoglobulin class switch recombination (CSR) to IgE is a tightly regulated process central to atopic disease. To profile the B-cell transcriptional responses underlying the activation of the germinal centre activities leading to the generation of IgE, naïve human B-cells were stimulated with IL-4...

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Detalles Bibliográficos
Autores principales: Zhang, Youming, Fear, David J., Willis-Owen, Saffron A. G., Cookson, William O., Moffatt, Miriam F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126563/
https://www.ncbi.nlm.nih.gov/pubmed/27897229
http://dx.doi.org/10.1038/srep37988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126563/
https://www.ncbi.nlm.nih.gov/pubmed/27897229
http://dx.doi.org/10.1038/srep37988

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