Mitochondrial control through nutritionally regulated global histone H3 lysine-4 demethylation

Histone demethylation by Jumonji-family proteins is coupled with the decarboxylation of α-ketoglutarate (αKG) to yield succinate, prompting hypotheses that their activities are responsive to levels of these metabolites in the cell. Consistent with this paradigm we show here that the Saccharomyces ce...

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Detalles Bibliográficos
Autores principales: Soloveychik, Maria, Xu, Mengshu, Zaslaver, Olga, Lee, Kwanyin, Narula, Ashrut, Jiang, River, Rosebrock, Adam P., Caudy, Amy A., Meneghini, Marc D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126570/
https://www.ncbi.nlm.nih.gov/pubmed/27897198
http://dx.doi.org/10.1038/srep37942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126570/
https://www.ncbi.nlm.nih.gov/pubmed/27897198
http://dx.doi.org/10.1038/srep37942

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