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ECM proteins in a microporous scaffold influence hepatocyte morphology, function, and gene expression

It is well known that a three-dimensional (3D) culture environment and the presence of extracellular matrix (ECM) proteins facilitate hepatocyte viability and maintenance of the liver-specific phenotype in vitro. However, it is not clear whether specific ECM components such as collagen or fibronecti...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Kim, Myung Hee, Shirahama, Hitomi, Lee, Jae Ho, Ng, Soon Seng, Glenn, Jeffrey S., Cho, Nam-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126637/
https://www.ncbi.nlm.nih.gov/pubmed/27897167
http://dx.doi.org/10.1038/srep37427