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ECM proteins in a microporous scaffold influence hepatocyte morphology, function, and gene expression
It is well known that a three-dimensional (3D) culture environment and the presence of extracellular matrix (ECM) proteins facilitate hepatocyte viability and maintenance of the liver-specific phenotype in vitro. However, it is not clear whether specific ECM components such as collagen or fibronecti...
Autores principales: | Wang, Yan, Kim, Myung Hee, Shirahama, Hitomi, Lee, Jae Ho, Ng, Soon Seng, Glenn, Jeffrey S., Cho, Nam-Joon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126637/ https://www.ncbi.nlm.nih.gov/pubmed/27897167 http://dx.doi.org/10.1038/srep37427 |
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