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Magnetofection Enhances Lentiviral-Mediated Transduction of Airway Epithelial Cells through Extracellular and Cellular Barriers

Gene transfer to airway epithelial cells is hampered by extracellular (mainly mucus) and cellular (tight junctions) barriers. Magnetofection has been used to increase retention time of lentiviral vectors (LV) on the cellular surface. In this study, magnetofection was investigated in airway epithelia...

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Detalles Bibliográficos
Autores principales: Castellani, Stefano, Orlando, Clara, Carbone, Annalucia, Di Gioia, Sante, Conese, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126789/
https://www.ncbi.nlm.nih.gov/pubmed/27886077
http://dx.doi.org/10.3390/genes7110103