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The E3 Ubiquitin Ligase TMEM129 Is a Tri-Spanning Transmembrane Protein
Misfolded proteins from the endoplasmic reticulum (ER) are transported back into the cytosol for degradation via the ubiquitin-proteasome system. The human cytomegalovirus protein US11 hijacks this ER-associated protein degradation (ERAD) pathway to downregulate human leukocyte antigen (HLA) class I...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127023/ https://www.ncbi.nlm.nih.gov/pubmed/27854284 http://dx.doi.org/10.3390/v8110309 |