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The E3 Ubiquitin Ligase TMEM129 Is a Tri-Spanning Transmembrane Protein

Misfolded proteins from the endoplasmic reticulum (ER) are transported back into the cytosol for degradation via the ubiquitin-proteasome system. The human cytomegalovirus protein US11 hijacks this ER-associated protein degradation (ERAD) pathway to downregulate human leukocyte antigen (HLA) class I...

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Detalles Bibliográficos
Autores principales:	van de Weijer, Michael L., van Muijlwijk, Guus H., Visser, Linda J., Costa, Ana I., Wiertz, Emmanuel J. H. J., Lebbink, Robert Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127023/ https://www.ncbi.nlm.nih.gov/pubmed/27854284 http://dx.doi.org/10.3390/v8110309

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