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Glutathione-Conjugates of Deoxynivalenol in Naturally Contaminated Grain Are Primarily Linked via the Epoxide Group

A glutathione (GSH) adduct of the mycotoxin 4-deoxynivalenol (DON), together with a range of related conjugates, has recently been tentatively identified by LC-MS of DON-treated wheat spikelets. In this study, we prepared samples of DON conjugated at the 10- and 13-positions with GSH, Cys, CysGly, γ...

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Detalles Bibliográficos
Autores principales: Uhlig, Silvio, Stanic, Ana, Hofgaard, Ingerd S., Kluger, Bernhard, Schuhmacher, Rainer, Miles, Christopher O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127126/
https://www.ncbi.nlm.nih.gov/pubmed/27845722
http://dx.doi.org/10.3390/toxins8110329