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Impact of Dendrimer Terminal Group Chemistry on Blockage of the Anthrax Toxin Channel: A Single Molecule Study

Nearly all the cationic molecules tested so far have been shown to reversibly block K(+) current through the cation-selective PA(63) channels of anthrax toxin in a wide nM–mM range of effective concentrations. A significant increase in channel-blocking activity of the cationic compounds was achieved...

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Detalles Bibliográficos
Autores principales: Yamini, Goli, Kalu, Nnanya, Nestorovich, Ekaterina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127133/
https://www.ncbi.nlm.nih.gov/pubmed/27854272
http://dx.doi.org/10.3390/toxins8110337