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Impact of Dendrimer Terminal Group Chemistry on Blockage of the Anthrax Toxin Channel: A Single Molecule Study
Nearly all the cationic molecules tested so far have been shown to reversibly block K(+) current through the cation-selective PA(63) channels of anthrax toxin in a wide nM–mM range of effective concentrations. A significant increase in channel-blocking activity of the cationic compounds was achieved...
Autores principales: | Yamini, Goli, Kalu, Nnanya, Nestorovich, Ekaterina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127133/ https://www.ncbi.nlm.nih.gov/pubmed/27854272 http://dx.doi.org/10.3390/toxins8110337 |
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