Monotreme glucagon-like peptide-1 in venom and gut: one gene – two very different functions

The importance of Glucagon like peptide 1 (GLP-1) for metabolic control and insulin release sparked the evolution of genes mimicking GLP-1 action in venomous species (e.g. Exendin-4 in Heloderma suspectum (gila monster)). We discovered that platypus and echidna express a single GLP-1 peptide in both...

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Detalles Bibliográficos
Autores principales: Tsend-Ayush, Enkhjargal, He, Chuan, Myers, Mark A., Andrikopoulos, Sof, Wong, Nicole, Sexton, Patrick M., Wootten, Denise, Forbes, Briony E., Grutzner, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127184/
https://www.ncbi.nlm.nih.gov/pubmed/27898108
http://dx.doi.org/10.1038/srep37744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127184/
https://www.ncbi.nlm.nih.gov/pubmed/27898108
http://dx.doi.org/10.1038/srep37744

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