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Monotreme glucagon-like peptide-1 in venom and gut: one gene – two very different functions
The importance of Glucagon like peptide 1 (GLP-1) for metabolic control and insulin release sparked the evolution of genes mimicking GLP-1 action in venomous species (e.g. Exendin-4 in Heloderma suspectum (gila monster)). We discovered that platypus and echidna express a single GLP-1 peptide in both...
Autores principales: | Tsend-Ayush, Enkhjargal, He, Chuan, Myers, Mark A., Andrikopoulos, Sof, Wong, Nicole, Sexton, Patrick M., Wootten, Denise, Forbes, Briony E., Grutzner, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127184/ https://www.ncbi.nlm.nih.gov/pubmed/27898108 http://dx.doi.org/10.1038/srep37744 |
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