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Insulin Downregulates the Transcriptional Coregulator CITED2, an Inhibitor of Proangiogenic Function in Endothelial Cells

In patients with atherosclerotic complications of diabetes, impaired neovascularization of ischemic tissue in the myocardium and lower limb limits the ability of these tissues to compensate for poor perfusion. We identified 10 novel insulin-regulated genes, among them Adm, Cited2, and Ctgf, which we...

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Detalles Bibliográficos
Autores principales: Wang, Xuanchun, Lockhart, Samuel M., Rathjen, Thomas, Albadawi, Hassan, Sørensen, Ditte, O'Neill, Brian T., Dwivedi, Nishant, Preil, Simone R., Beck, Hans Christian, Dunwoodie, Sally L., Watkins, Michael T., Rasmussen, Lars Melholt, Rask-Madsen, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127242/
https://www.ncbi.nlm.nih.gov/pubmed/27561725
http://dx.doi.org/10.2337/db16-0001