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Topical Prostaglandin E Analog Restores Defective Dendritic Cell–Mediated Th17 Host Defense Against Methicillin-Resistant Staphylococcus Aureus in the Skin of Diabetic Mice

People with diabetes are more prone to Staphylococcus aureus skin infection than healthy individuals. Control of S. aureus infection depends on dendritic cell (DC)–induced T-helper 17 (Th17)–mediated neutrophil recruitment and bacterial clearance. DC ingestion of infected apoptotic cells (IACs) driv...

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Detalles Bibliográficos
Autores principales: Dejani, Naiara N., Brandt, Stephanie L., Piñeros, Annie, Glosson-Byers, Nicole L., Wang, Sue, Son, Young Min, Medeiros, Alexandra I., Serezani, C. Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127243/
https://www.ncbi.nlm.nih.gov/pubmed/27605625
http://dx.doi.org/10.2337/db16-0565