Interaction of PPARα With the Canonic Wnt Pathway in the Regulation of Renal Fibrosis

Peroxisome proliferator–activated receptor-α (PPARα) displays renoprotective effects with an unclear mechanism. Aberrant activation of the canonical Wnt pathway plays a key role in renal fibrosis. Renal levels of PPARα were downregulated in both type 1 and type 2 diabetes models. The PPARα agonist f...

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Detalles Bibliográficos
Autores principales: Cheng, Rui, Ding, Lexi, He, Xuemin, Takahashi, Yusuke, Ma, Jian-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127249/
https://www.ncbi.nlm.nih.gov/pubmed/27543085
http://dx.doi.org/10.2337/db16-0426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127249/
https://www.ncbi.nlm.nih.gov/pubmed/27543085
http://dx.doi.org/10.2337/db16-0426

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