Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism

Impaired GLUT4-dependent glucose uptake is a contributing factor in the development of whole-body insulin resistance in obese patients and obese animal models. Previously, we demonstrated that transgenic mice engineered to express the human GLUT4 gene under the control of the human GLUT4 promoter (i...

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Detalles Bibliográficos
Autores principales: Gurley, Jami M., Ilkayeva, Olga, Jackson, Robert M., Griesel, Beth A., White, Phillip, Matsuzaki, Satochi, Qaisar, Rizwan, Van Remmen, Holly, Humphries, Kenneth M., Newgard, Christopher B., Olson, Ann Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127250/
https://www.ncbi.nlm.nih.gov/pubmed/27679559
http://dx.doi.org/10.2337/db16-0709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127250/
https://www.ncbi.nlm.nih.gov/pubmed/27679559
http://dx.doi.org/10.2337/db16-0709

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