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Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism
Impaired GLUT4-dependent glucose uptake is a contributing factor in the development of whole-body insulin resistance in obese patients and obese animal models. Previously, we demonstrated that transgenic mice engineered to express the human GLUT4 gene under the control of the human GLUT4 promoter (i...
Autores principales: | Gurley, Jami M., Ilkayeva, Olga, Jackson, Robert M., Griesel, Beth A., White, Phillip, Matsuzaki, Satochi, Qaisar, Rizwan, Van Remmen, Holly, Humphries, Kenneth M., Newgard, Christopher B., Olson, Ann Louise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127250/ https://www.ncbi.nlm.nih.gov/pubmed/27679559 http://dx.doi.org/10.2337/db16-0709 |
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