Kinase Inhibition Leads to Hormesis in a Dual Phosphorylation-Dephosphorylation Cycle

Many antimicrobial and anti-tumour drugs elicit hormetic responses characterised by low-dose stimulation and high-dose inhibition. While this can have profound consequences for human health, with low drug concentrations actually stimulating pathogen or tumour growth, the mechanistic understanding be...

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Detalles Bibliográficos
Autores principales: Rashkov, Peter, Barrett, Ian P., Beardmore, Robert E., Bendtsen, Claus, Gudelj, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127489/
https://www.ncbi.nlm.nih.gov/pubmed/27898662
http://dx.doi.org/10.1371/journal.pcbi.1005216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127489/
https://www.ncbi.nlm.nih.gov/pubmed/27898662
http://dx.doi.org/10.1371/journal.pcbi.1005216

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