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Kinase Inhibition Leads to Hormesis in a Dual Phosphorylation-Dephosphorylation Cycle
Many antimicrobial and anti-tumour drugs elicit hormetic responses characterised by low-dose stimulation and high-dose inhibition. While this can have profound consequences for human health, with low drug concentrations actually stimulating pathogen or tumour growth, the mechanistic understanding be...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127489/ https://www.ncbi.nlm.nih.gov/pubmed/27898662 http://dx.doi.org/10.1371/journal.pcbi.1005216 |