Targeting CDKs with Roscovitine Increases Sensitivity to DNA Damaging Drugs of Human Osteosarcoma Cells

Cyclin-dependent kinase 2 (CDK2) has been reported to be essential for cell proliferation in several human tumours and it has been suggested as an appropriate target to be considered in order to enhance the efficacy of treatment regimens based on the use of DNA damaging drugs. We evaluated the clini...

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Detalles Bibliográficos
Autores principales: Vella, Serena, Tavanti, Elisa, Hattinger, Claudia Maria, Fanelli, Marilù, Versteeg, Rogier, Koster, Jan, Picci, Piero, Serra, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127503/
https://www.ncbi.nlm.nih.gov/pubmed/27898692
http://dx.doi.org/10.1371/journal.pone.0166233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127503/
https://www.ncbi.nlm.nih.gov/pubmed/27898692
http://dx.doi.org/10.1371/journal.pone.0166233

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