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Aberrations in the Iron Regulatory Gene Signature Are Associated with Decreased Survival in Diffuse Infiltrating Gliomas

Iron is a tightly regulated micronutrient with no physiologic means of elimination and is necessary for cell division in normal tissue. Recent evidence suggests that dysregulation of iron regulatory proteins may play a role in cancer pathophysiology. We use public data from The Cancer Genome Atlas (...

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Detalles Bibliográficos
Autores principales: Weston, Cody, Klobusicky, Joe, Weston, Jennifer, Connor, James, Toms, Steven A., Marko, Nicholas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127508/
https://www.ncbi.nlm.nih.gov/pubmed/27898674
http://dx.doi.org/10.1371/journal.pone.0166593