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Chemokine Levels in the Penile Coronal Sulcus Correlate with HIV-1 Acquisition and Are Reduced by Male Circumcision in Rakai, Uganda
Individual susceptibility to HIV is heterogeneous, but the biological mechanisms explaining differences are incompletely understood. We hypothesized that penile inflammation may increase HIV susceptibility in men by recruiting permissive CD4 T cells, and that male circumcision may decrease HIV susce...
Autores principales: | Prodger, Jessica L., Gray, Ronald H., Shannon, Brett, Shahabi, Kamnoosh, Kong, Xiangrong, Grabowski, Kate, Kigozi, Godfrey, Nalugoda, Fred, Serwadda, David, Wawer, Maria J., Reynolds, Steven J., Liu, Cindy M., Tobian, Aaron A. R., Kaul, Rupert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127584/ https://www.ncbi.nlm.nih.gov/pubmed/27898732 http://dx.doi.org/10.1371/journal.ppat.1006025 |
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