Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation

Heat shock factor (Hsf1) regulates the expression of molecular chaperones to maintain protein homeostasis. Despite its central role in stress resistance, disease and aging, the mechanisms that control Hsf1 activity remain unresolved. Here we show that in budding yeast, Hsf1 basally associates with t...

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Detalles Bibliográficos
Autores principales: Zheng, Xu, Krakowiak, Joanna, Patel, Nikit, Beyzavi, Ali, Ezike, Jideofor, Khalil, Ahmad S, Pincus, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127643/
https://www.ncbi.nlm.nih.gov/pubmed/27831465
http://dx.doi.org/10.7554/eLife.18638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127643/
https://www.ncbi.nlm.nih.gov/pubmed/27831465
http://dx.doi.org/10.7554/eLife.18638

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