Structural basis for the recognition of spliceosomal SmN/B/B’ proteins by the RBM5 OCRE domain in splicing regulation

The multi-domain splicing factor RBM5 regulates the balance between antagonistic isoforms of the apoptosis-control genes FAS/CD95, Caspase-2 and AID. An OCRE (OCtamer REpeat of aromatic residues) domain found in RBM5 is important for alternative splicing regulation and mediates interactions with com...

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Detalles Bibliográficos
Autores principales: Mourão, André, Bonnal, Sophie, Soni, Komal, Warner, Lisa, Bordonné, Rémy, Valcárcel, Juan, Sattler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127646/
https://www.ncbi.nlm.nih.gov/pubmed/27894420
http://dx.doi.org/10.7554/eLife.14707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127646/
https://www.ncbi.nlm.nih.gov/pubmed/27894420
http://dx.doi.org/10.7554/eLife.14707

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