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Scaling probabilistic models of genetic variation to millions of humans

A major goal of population genetics is to quantitatively understand variation of genetic polymorphisms among individuals. The aggregated number of genotyped humans is currently on the order millions of individuals, and existing methods do not scale to data of this size. To solve this problem we deve...

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Detalles Bibliográficos
Autores principales: Gopalan, Prem, Hao, Wei, Blei, David M., Storey, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127768/
https://www.ncbi.nlm.nih.gov/pubmed/27819665
http://dx.doi.org/10.1038/ng.3710