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IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity

Plasmacytoid dendritic cells (pDCs) have been shown to both mediate and prevent autoimmunity, and the regulation of their immunogenic versus tolerogenic functions remains incompletely understood. Here we demonstrate that, compared to other cells, pDCs are the major expressors of Indoleamine-2,3-diox...

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Detalles Bibliográficos
Autores principales: Lippens, Carla, Duraes, Fernanda V., Dubrot, Juan, Brighouse, Dale, Lacroix, Mathilde, Irla, Magali, Aubry-Lachainaye, Jean-Pierre, Reith, Walter, Mandl, Judith N., Hugues, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127883/
https://www.ncbi.nlm.nih.gov/pubmed/27470005
http://dx.doi.org/10.1016/j.jaut.2016.07.004