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IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity
Plasmacytoid dendritic cells (pDCs) have been shown to both mediate and prevent autoimmunity, and the regulation of their immunogenic versus tolerogenic functions remains incompletely understood. Here we demonstrate that, compared to other cells, pDCs are the major expressors of Indoleamine-2,3-diox...
Autores principales: | Lippens, Carla, Duraes, Fernanda V., Dubrot, Juan, Brighouse, Dale, Lacroix, Mathilde, Irla, Magali, Aubry-Lachainaye, Jean-Pierre, Reith, Walter, Mandl, Judith N., Hugues, Stéphanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127883/ https://www.ncbi.nlm.nih.gov/pubmed/27470005 http://dx.doi.org/10.1016/j.jaut.2016.07.004 |
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