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Antimicrobial activity and stability of the d-amino acid substituted derivatives of antimicrobial peptide polybia-MPI
Antimicrobial peptide has the potential to be developed as new kind of antimicrobial agents with novel action mechanism. However, the susceptibility to protease is a drawback for potential peptides to be clinical used. d-amino acid substitution can be one way to increase the proteolytic stability of...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128008/ https://www.ncbi.nlm.nih.gov/pubmed/27900727 http://dx.doi.org/10.1186/s13568-016-0295-8 |