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Antimicrobial activity and stability of the d-amino acid substituted derivatives of antimicrobial peptide polybia-MPI

Antimicrobial peptide has the potential to be developed as new kind of antimicrobial agents with novel action mechanism. However, the susceptibility to protease is a drawback for potential peptides to be clinical used. d-amino acid substitution can be one way to increase the proteolytic stability of...

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Detalles Bibliográficos
Autores principales: Zhao, Yanyan, Zhang, Min, Qiu, Shuai, Wang, Jiayi, Peng, Jinxiu, Zhao, Ping, Zhu, Ranran, Wang, Hailin, Li, Yuan, Wang, Kairong, Yan, Wenjin, Wang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128008/
https://www.ncbi.nlm.nih.gov/pubmed/27900727
http://dx.doi.org/10.1186/s13568-016-0295-8