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Control of NFAT Isoform Activation and NFAT-Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca(2+) Signals

Excitation-transcription coupling, linking stimulation at the cell surface to changes in nuclear gene expression, is conserved throughout eukaryotes. How closely related coexpressed transcription factors are differentially activated remains unclear. Here, we show that two Ca(2+)-dependent transcript...

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Detalles Bibliográficos
Autores principales: Kar, Pulak, Mirams, Gary R., Christian, Helen C., Parekh, Anant B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128683/
https://www.ncbi.nlm.nih.gov/pubmed/27863227
http://dx.doi.org/10.1016/j.molcel.2016.11.011